Industrial applications of functional fatty acids produced by gut lactic acid bacteria

Yasunori Yonejima Nitto Pharma, Kyoto Nitto Pharma supply seven strains of gut lactic acid bacteria for food materials under the NOSTER brand and retains more than 400 strains in its library. The company is pursuing open innovation ‘postbiotics’ research in the search for metabolites from gut microbes to promote scientific advances in bioactive metabolites and

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LipoQuality project: Advanced lipidomics strategy to identify bioactive lipids

Makoto Arita, Ph.D. Laboratory for Metabolomics, RIKEN-IMS Graduate School of Pharmaceutical Sciences, Keio University Graduate School of Medical Life Science, Yokohama City University Makoto Arita is a principal investigator of the ‘LipoQuality’ project in JSPS Grant-in-Aid for Scientific Research on Innovative Areas, that focuses on the mechanisms in which specific molecular species of lipids, namely

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Role of lactic acid microbes in defense against infection: Exopolysaccharide produced by Leuconostoc mesenteroides enhances antigen-specific IgA secretion

Antigen-specific immunoglobulin A (IgA) plays a salient role in host defense against mucosal infection. We reported earlier that exopolysaccharide (EPS) produced by probiotic Leuconostoc mesenteroides strain NTM048 can enhance mucosal IgA production in mice. However, the capability of enhancing antigen-specific IgA production remains unclear. Here, Chiaki Matsuzaki of Ishikawa Prefectural University and colleagues in Japan

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Clinical application of postbiotics in the treatment of Helicobacter infections

Liquid HYA HYA-fatty acid combats bacterial gastric diseases in mouse model experiments The human digestive system is host to many kinds of bacteria: some friendly, probiotics types, and other kinds that are harmful. Identifying metabolic processes that can differentiate between these two types of bacteria is important to develop treatments for diseases caused by unfriendly

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Advances in postbiotics research for healthcare

Graph showing changes in blood glucose level in all subjects after ingestion. Clinical trials with fatty acid (HYA) derived from probiotic bacteria show potential health benefits in treating metabolic disorders Metabolic syndrome is a set of conditions including obesity and hypertension that could potentially lead to heart disease and diabetes. Reported cases of metabolic syndrome

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